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28
March
2024
|
12:50
Europe/London

91直播 researchers help secure 拢49.35m to boost mass spectrometry research

Scientists at The University of Manchester have supported a successful bid for a new distributed research and innovation infrastructure aimed at bolstering the UK鈥檚 capability in mass spectrometry.

The bid was delivered by a coordination team, which includes and from the University and has secured 拢49.35m from the UKRI Infrastructure Fund to establish C-MASS - a national hub-and-spoke infrastructure designed to integrate and advance the country鈥檚 capability in mass spectrometry.

Mass spectrometry is a central analytical technique that quantifies and identifies molecules by measuring their mass and charge. It is used across science and medicine, for drug discovery, to screen all newborn babies for the presence of metabolic disorders, to monitor pollution and to tell us what compounds are in the tails of comets.

Researchers at The University of Manchester develop and apply mass spectrometry in many of its research centres and institutes, including the , the , , , the , and the

C-MASS will enable rapid methodological advances, by developing consensus protocols to allow population level screening of health markers and accelerated data access and sharing. It will bring together cutting-edge instrumentation at a range of laboratories connected by a coordinating central hub that will manage a central metadata catalogue. Together, this will provide unparalleled signposting of data and will be a critical measurement science resource for the UK.

The bid for the funding has been developed over the last 10 years and has included input and support from more than 40 higher education institutes, 35 industrial partners and numerous research institutes.

鈥淎s part of the coordination team for this bid, I am absolutely delighted. C-Mass will be a distributed infrastructure to enhance the capabilities of mass spectrometry across the UK and grant us unprecedented insights to the molecules that make up our world.鈥
 

Professor Perdita Barran, Director of the Michael Barber Centre for Collaborative Mass Spectrometry at The University of Manchester

91直播 is renowned for its expertise in mass spectrometry. J.J. Thomson, who was an alumnus of The University of Manchester, built the first mass spectrometer - originally called a parabola spectrograph - in 1912. Later, another alumnus, James Chadwick, commissioned the first commercial mass spectrometer, built by the 91直播 firm Metropolitan Vickers, for use in the second world war to separate radioactive isotopes.

Now, many decades later, the University receives more funding in mass spectrometry than any other higher education institution in the UK and more mass spectrometers are made in the 91直播 region than any other in Europe.

At the University, researchers across a range of disciplines including , , use mass spectrometry for wide range of world-leading research. Just some of those projects include: , improving the testing and diagnosis of womb cancer, improving our understanding of Huntington鈥檚 disease and rheumatic heart disease, diagnosing Parkinson鈥檚 disease and finding treatments for blindness.

The mass spectrometry laboratories at the University boast a range of industry-leading instrumentations, not just for staff and students, but also collaborating with many external companies. 

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